Once in awhile, speaking Italian comes in handy.  Here's my contribution to the nickname brigade, through a literal Italian reading of Nocioni's name.

In Italian noce = nut (or walnut).  The suffix -one makes the noun that it's attached to "big."  Like a bacio is a kiss, and a bacione is a big kiss.  So a nocione is thus a "big nut."  And to pluralize, Italian does not append -s to the end of the noun.  If the noun ends in an -e, then that -e becomes an -i to indicate the plural.  Thus you have one nocione and two nocioni.  There we have it, nocioni means "big nuts."

Andres "Big Nuts" Nocioni.  Now he just has to drain a couple game winners to justify the nickname.